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Material Data Safety Sheet HEADING_TITLE
 

Coating Systems Laboratories, Inc.

211 E. Chilton Drive, Chandler, AZ 85225

PATHOGENS INACTIVATED BY GERM FREE 24/ZERO PLUS HAND SANITIZER
& PROTECTANT
[Octadecyldimethyl-3-(trihydroxysilylpropyl)ammonium chloride]
U.S.Patent No. 6,613,755

Gram Positive Bacteria

Reference

Bacillus sp. (vegetative cell)

5, 6, 11

Corynebacterium diptheriae

1,13

Micrococcus lutea

5, 6, 11

Micrococcus sp.

2, 5, 15

Mycobacterium tuberculosis

14

Mycobacterium smegmatis

14

Propionibacterium acnes

5

Staphylococcus aureus * **

2, 3, 5, 6, 10,

11,

13,

24,

15, 21

Staphylococcus epidermidis

2, 5, 6, 7, 11,

13,

14,

15

Streptococcus faecalis**

2, 5, 6, 7, 11,

13,

14

Streptococcus mutans

5, 6, 7, 11

Streptococcus pneumonia

1

Streptococcus pyogenes

5, 6, 7, 11

Gram Negative Bacteria

Acinetobacter calcoaceticus

2, 5, 6, 11, 14, 15

Aeromonas hydrophilia

5, 6, 11

Citrobacter deversus**

5, 6, 11

Citrobacter freundi

5, 6, 11

Enterobacter aerogenes

5, 6, 7, 11

Enterobacter aglomerans

2, 5, 14, 15

Enterobacter cloacae

5, 6, 7, 11

Enterococcus*

10

Escherichia coli*

1, 2, 3, 5, 6, 7, 10, 11, 13, 14

Klebsiella oxytoca*

5,6,11,14

Klebsiella pneumoniae

3, 5, 6, 7, 9, 10, 11, 13, 14

Klebsiella terriena

19

Legionella pneumophila

1

Morganella morganii

5, 6, 7, 11

Proteus mirabilis**

5, 6, 7, 11

Proteus vulgaris

5, 6, 7, 11

Pseudomonas aeruginosa*

2, 3, 5, 6, 7, 11,

13, 14

Pseudomonas fluorscens*

5, 6, 7, 10, 11

Salmonella cholera suis

5, 6, 7, 11, 14

Salmonella typhi

5, 6, 7, 11, 14

Salmonella typhimurium

1,5,6,7,11

Serratia liquifaciens

5, 6, 7, 11

Serratia marcescens

5, 6, 7, 11

Xanthomonas campestris

5, 6, 7, 11

Viruses

Adenovirus Type II & IV

17, 18, 21

Bovine Adenovirus Type I & IV

17, 18,21

Feline pneumonitis

21

Herpes Simplex Type I

16, 17,18

Herpes Simplex Type II

21

HIV-I(AIDS)

21

Influenza A2 (Aichi)

17, 18,21

Influenza A2 (Asian)

17,18

Influenza B

17,18

Mumps

17, 18

Parinfluenza (Sendai)

21

Rous Sarcoma

17,18

Reovirus Type I

17,18

Simian Virus 40

17, 18

Vaccinia

17,18

MS2

19

PRD1

19

Fungi, Algae, Mold, Yeast, Spores

Alterania alternata

8,12

Aspergillus flavus

2, 5, 6, 7, 11, 14

Aspergillus niger

2, 5, 6, 7, 8, 11,

12,13,

14

Aspergillus sydowi

5, 6, 7, 11

Aspergillus terreus

5, 6, 7, 11, 14

Aspergillus versicolor

2, 5, 6, 7, 11

Aspergillus verrucaria

14

Aureobasidium pullans

5, 6, 7, 8, 11, 12

Candida albicans

1, 2, 5, 6, 7,14

Candida pseudotropocalis

5, 6, 7, 11

Chaetomium globsum

1

Cladosporium cladosporioides

8,12

Chlorella vulgaris

19


Dreschslera australiensis

8,12

Epidermophyton sp.

9

Gliomastix cerealis

8,12

Gloeophyllum trabeum

5, 6, 7,

11

Microsporum sp.

9

Microsporum audouinii

21

Monilia grisea

8, 12

Oscillatoria

20

Penicillium chrysogenum

5, 6, 7,

11

Pencillium commune

8,12

Penicillium funiculosum

1, 2, 5,

6, 7, 11,

14

Penicillium pinophilium

5, 6, 7,

11

Penicillium variable

5, 6, 7,

11, 14

Phoma fimeti

8,12

Pithomyces chartarum

8,12

Poria placenta

5, 6, 7, 11

Scenedesmus

20

Saccharonyces cerevisiae

5,6,7,11,13,14

Scolecobasidium humicola

8, 12

Trichoderma viride

5, 6, 7, 11

Trichophyton interdigitale

2,14

Trichophyton maidson

14

Trichophyton mentogrophytes

5, 6, 7, 9, 11

Trichophyton sp.

9

Protozoa Parasites

Cryptosporidium parvum (oocysts)

19

REFERENCES

1. Y. Hsiao, Chinese Pat. Appl., PCT/CN98/00207 (1998)

2. James Malek, John Speir, " Method of Reducing the Number of Microorganisms in a Method of Preservation"; U.S. Pat. 4,259,103 (1981)

3. Stewart Klein, "3-(trimethoxysilyl)propyldidecylmethyl Ammonium Salts and Method of Inhibiting growth of Microorganisms Therewith"; U.S. Pat. 4,394,378 (1983).

4. William Eudy, "Organosilicon Quaternary Ammonium Antimicrobial Compounds"; U.S. Pat. 4,406892 (1983).

5. Richard Gettings, William White, "Skin Treatment Method"; U.S. Pat. 4,908,355.(1990)

6. Lynne Blank, William White, "Antimicrobial Rinse Cycle Additive"; U.S. Pat. 5,145,596 (1992)

7. Richard Gettings, William White, "Opthalmic fluid Dispensing Method"; U.S. Pat. 5,013,459 (1991).

8. Richard Avery, Frederick Martin, Sean Dwyer, "Production of Stable Hydrolyzable Organosilane Solutions"; U.S. Pat. 5,411,585 (1995).

9. Lynne Blank, Richard Gettings, William White, "Method of Treating Tinea Pedis and Related Dermatophytic Infections"; U.S. Pat. 4,865,844 (1989).

10. David Battice, Michael Hale, "Antimicrobially Effective Organic Foams and Methods for their Preparation"; U.S. Pat. 4,631,297 (1986).

11. Bruce Higgs, William White, "Solid Antimicrobial"; U.S. Pat. 5,359,104 (1994). This patent also describes the method of antimicrobial activity.

12. Richard Avery, Frederick Martin, Sean Dwyer, Colin Brown, "Production of
Stable Hydrolyzable Organosilane Solutions"; U.S. Pat. 5,411,585 (1995).

13. William White, Jerry Olderman, "Anitimicrobial Techniques for Medical Nonwovens: A Case Study"; Book of Papers, 1984,12 1h Annual Nonwovens Tech. Symposium, pp. 13-46. No bacterial adaption (no increased bacterial resistance to

Zoonocide) reported.

14. J. McGee, J. Malek, W. White, "New Antimicrobial Treatment for Carpet Applications", Am. Dyestuff Rep., 1983, (6), pp.56-59. Dow corning Technical Brochure; 22-994-83 (1983).

15. Richard Gettings, Benny Triplett, "A New Durable Antimicrobial Finish for Textiles"; Book of Papers, 1978, American Association of Textile Chemists and Colorists National Technical Conference, pp. 259-261. Dow Corning Technical Brochure; 24-095-85 (1985).

16. I-Fu Tsao, Henry Wang, Charles Shipman, "Interaction of Infectious Viral Particles with a Quaternary Ammonium Chloride Surface"; Biotechnol. Bioeng., 34, (5), pp. 639-46 (1989).

17.11-Fu Tsao, Henry Wang, "Removal and Inactivation of Viruses by a Surface 'Bonded Quaternary Ammonium Chloride", ACS Synp.Ser. (1990), Volume Date 1988, 419, pp. 250-67. Reaction with Lipidophilic Viruses.

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